What disease does the laird have in Outlander? His older brother, Colum, is the ruling laird, but he would be nothing without Dougal. Colum suffers from a condition now known as Toulouse-Lautrec Syndrome, a degenerative disease that renders his legs immobile at times and fills his days with great physical pain.
What disability did Toulouse-Lautrec have? Toulouse-Lautrec suffered with health conditions for all of his life; he fractured both of his legs as a teenager and these never healed, leaving it to be widely believed that he suffered from a congenital bone disease. While he developed an adult-sized torso, his legs never grew beyond those of a child.
What causes Melorheostosis? What causes melorheostosis? In about 1 in 2 cases, melorheostosis occurs because of a change (mutation) in the MAP2K1 gene. The MAP2K1 gene makes a specific protein that controls how bone cells grow. This gene change happens randomly (sporadically).
Did Toulouse-Lautrec have osteogenesis imperfecta? Lautrec’s parents were nobles and his first cousins, likely giving him a rare congenital condition known as osteogenesis imperfecta. In his teen years, he was more prone to bone fractures and broke both of his legs.